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RO7567132 Antibody

RO7567132 (FAP-LTBR) is a bispecific antibody that locally agonizes LTBR and antagonizes FAP within tumors, promoting tertiary lymphoid structure (TLS) formation while minimizing systemic effects. Preclinical studies in mouse models of breast and colorectal cancer demonstrate its ability to enhance immune infiltration and inhibit tumor growth, particularly in combination with anti-PD-L1 therapy.

Product Specifications

Target

TNF

Clonality

Recombinant

Conjugation

Unconjugated

Field of Research

Cell Biology

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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