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Epipodophyllotoxin acetate

Epipodophyllotoxin acetate (4-O-Epipodophyllotoxinyl acetate; compound 4) is a cyclolignan that exhibits antineoplastic and antiviral activities. Epipodophyllotoxin acetate inhibits HSV and VSV, with IC50s of 0.2 and 0.1 μg/mL, respectively[1].

Product Specifications

CAS Number

[1180-35-4]

Product Name Alternative

4-O-Epipodophyllotoxinyl acetate

UNSPSC

12352005

Target

HSV; VSV

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/epipodophyllotoxin-acetate.html

Solubility

10 mM in DMSO

Smiles

O=C1[C@]2([H])[C@H](C3=CC(OC)=C(C(OC)=C3)OC)C4=CC(OCO5)=C5C=C4[C@H]([C@@]2([H])CO1)OC(C)=O

Molecular Formula

C24H24O9

Molecular Weight

456.44

References & Citations

[1]Feliciano AS, et, al. Antineoplastic and antiviral activities of some cyclolignans. Planta Med. 1993 Jun;59 (3) :246-9.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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