Clomipramine-d3
Clomipramine-d3 is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].
Product Specifications
CAS Number
136765-29-2
Product Name Alternative
Chlorimipramine-d3; G-34586-d3; NSC-169865-d3
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Dopamine Receptor; Isotope-Labeled Compounds; Serotonin Transporter
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
ClC1=CC2=C(C=C1)CCC3=C(C=CC=C3)N2CCCN(C([2H])([2H])[2H])C
Molecular Formula
C19H20D3ClN2
Molecular Weight
317.87
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
References & Citations
[1]McTavish, D. and P. Benfield, Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs, 1990. 39 (1) : p. 136-53.|[2]Owens, M.J., et al., Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther, 1997. 283 (3) : p. 1305-22.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
D3 Receptor
Available Sizes
Frequently Asked Questions
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