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Clomipramine-d3

Clomipramine-d3 is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].

Product Specifications

CAS Number

136765-29-2

Product Name Alternative

Chlorimipramine-d3; G-34586-d3; NSC-169865-d3

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Dopamine Receptor; Isotope-Labeled Compounds; Serotonin Transporter

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Solubility

10 mM in DMSO

Smiles

ClC1=CC2=C(C=C1)CCC3=C(C=CC=C3)N2CCCN(C([2H])([2H])[2H])C

Molecular Formula

C19H20D3ClN2

Molecular Weight

317.87

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

References & Citations

[1]McTavish, D. and P. Benfield, Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs, 1990. 39 (1) : p. 136-53.|[2]Owens, M.J., et al., Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther, 1997. 283 (3) : p. 1305-22.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Isoform

D3 Receptor

Available Sizes

Frequently Asked Questions

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