OICR-9429-N-C2-NH2
Product Specifications
UNSPSC Description
OICR-9429-N-C2-NH2 is a ligand for Wd40 repeat domain protein 5 (WDR5) extracted from patent WO2019246570A1, intermediate 2. OICR-9429-N-C2-NH2 can be used in the synthesis of PROTACs[1].
Target Antigen
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oicr-9429-n-c2-nh2.html
Solubility
10 mM in DMSO
Smiles
CN(CC1)CCN1C(C(NC(C2=CNC(C=C2C(F)(F)F)=O)=O)=C3)=CC=C3C4=CC(CN5CCN(CCN)CC5)=CC=C4
Molecular Weight
597.67
References & Citations
[1]Jin J, et, al. Wd40 repeat domain protein 5 (wdr5) degradation / disruption compounds and methods of use. WO2019246570A1.|[2]Chung CW, et, al. Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. ACS Chem Biol. 2020 Sep 18;15(9):2316-2323.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141798/OICR-9429-N-C2-NH2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141798/
Clinical Information
No Development Reported
CAS Number
2407457-55-8
Available Sizes
Curated Selection
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