Naa50-IN-1

Naa50-IN-1 (Compound 4a) is a specific N-α-Acetyltransferase 50 (Naa50) inhibitor (IC50=7 nM) . Naa50-IN-1 has potential in cancer research[1].

Product Specifications

CAS Number

[2522920-65-4]

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/naa50-in-1.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C2=NN=NN2)C=C1)N3[C@H](C4=NC(C(NC)=O)=CS4)C[C@@H](C3)NC([C@@H]5CC(N(C(N5)=O)C)=O)=O

Molecular Formula

C23H24N10O5S

Molecular Weight

552.57

References & Citations

[1]Kung PP, et al. Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library. ACS Med Chem Lett. 2020 Apr 10;11 (6) :1175-1184.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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