Ac5GalNTGc
Ac5GalNTGc is a potent, peracetylated C-2 thioglycolyl-substituted GalNAc analog that efficiently inhibits mucin-type O-glycan biosynthesis. Ac5GalNTGc reduces leukocyte sialyl-Lewis-X expression and inhibits L-/P-selectin mediated rolling under flow, as well as P-selectin dependent leukocyte-platelet adhesion. Ac5GalNTGc exhibits anti-inflammatory activity in a thioglycollate-induced acute peritonitis model. Ac5GalNTGc can be used for studies of O-glycan/mucin biology, inflammation, and related translational research[1][2].
Product Specifications
UNSPSC
12352005
Target
Mucin
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ac5galntgc.html
Purity
98.39
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(O[C@@H]1[C@H]([C@@H](O[C@@H]([C@@H]1OC(C)=O)COC(C)=O)OC(C)=O)NC(CSC(C)=O)=O)=O
Molecular Formula
C18H25NO11S
Molecular Weight
463.46
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
SOX2 (Embryonic Stem Cell Marker) (rSOX2/1792), CF488A conjugate, 0.1mg/mL
![C1QA Recombinant Rabbit Monoclonal Antibody [JE66-59]](https://cdn.genprice.uk/products/992/68dd1c8d061270361ea820ce/imageurl/ha721439.webp)
C1QA Recombinant Rabbit Monoclonal Antibody [JE66-59]
Descyclopropyl Bexagliflozin Carboxylic Acid
