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(+) - (3R,8S) -Falcarindiol

(+) - (3R,8S) -Falcarindiol is a polyacetylene found in carrots, has antimycobacterial activity, with an IC50 of 6 μM and MIC of 24 μM against Mycobacterium tuberculosis H37Ra[1][2]. Antineoplastic and anti-inflammatory activity[2]. (+) - (3R,8S) -Falcarindiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

225110-25-8

Product Name Alternative

(3R,8S) -Falcarindiol; 3 (R),8 (S),9 (Z) -Falcarindiol

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/3r-8s-falcarindiol.html

Purity

99.88

Solubility

DMSO : 150 mg/mL (ultrasonic)

Smiles

C=C[C@@H](O)C#CC#C[C@@H](O)/C=C\CCCCCCC

Molecular Formula

C17H24O2

Molecular Weight

260.37

Precautions

H302, H315, H319, H335

References & Citations

[1]O'Neill T, et al. The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarins. J Ethnopharmacol. 2013 May 2;147 (1) :232-7.|[2]Kobaek-Larsen M, et al. Effect of the dietary polyacetylenes falcarinol and falcarindiol on the gut microbiota composition in a rat model of colorectal cancer. BMC Res Notes. 2018 Jun 27;11 (1) :411.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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