3,7,4'-Trihydroxyflavone

3,7,4'-Trihydroxyflavone (5-Deoxykampferol) is a flavonoid compound that can be isolated from the stems of Rhus javanica var. roxburghiana. 3,7,4'-Trihydroxyflavone has the effect of cleaving DNA in the presence of copper ions. 3,7,4'-Trihydroxyflavone also has anti-inflammatory and antioxidant activities and can scavenge various reactive oxygen species (ROS) and reactive nitrogen species (RNS) [1][2].

Product Specifications

CAS Number

[2034-65-3]

Product Name Alternative

5-Deoxykampferol; Resokaempferol

UNSPSC

12352005

Target

DNA/RNA Synthesis; Leukotriene Receptor; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/3,7,4_acute_-Trihydroxyflavone.html

Concentration

10mM

Purity

99.44

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C(O)=C(C2=CC=C(O)C=C2)OC3=CC(O)=CC=C13

Molecular Formula

C15H10O5

Molecular Weight

270.24

References & Citations

[1]Lin CN, et al. Flavonoids with DNA strand-scission activity from Rhus javanica var. roxburghiana. Fitoterapia. 2008 Jan;79 (1) :32-6. Epub 2007 Aug 9.|[2]Gomes A, et al. Trihydroxyflavones with antioxidant and anti-inflammatory efficacy. Biofactors. 2012 Sep-Oct;38 (5) :378-86.