PI3K/AKT-IN-2
PI3K/AKT-IN-2 (Compound 12c) is a PI3K and AKT inhibitor. PI3K/AKT-IN-2 blocks the epithelial-mesenchymal transition (EMT) and induces apoptosis. PI3K/AKT-IN-2 inhibits the polymerization of tubulin[1].
Product Specifications
CAS Number
[2684412-41-5]
UNSPSC
12352005
Target
Akt; Apoptosis; Microtubule/Tubulin; MMP; PI3K
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton; Metabolic Enzyme/Protease; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3k-akt-in-2.html
Purity
98.10
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O[C@@H]1[C@]2([H])[C@@](C(OC2)=O)([H])[C@H](C3=CC(OC)=C(OC)C(OC)=C3)C4=C1C=C5OCOC5=C4)/C=C/C(C6=CC=C(Br)C=C6)=O
Molecular Formula
C32H27BrO10
Molecular Weight
651.45
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-2
Available Sizes
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