Chlorotoxin

<strong>Chlorotoxin</strong> <strong>Catalog number:</strong> MDP0652 <strong>CAS Number: </strong>202801-92-1 <strong>Sequence: </strong>Met-Cys-Met-Pro-Cys-Phe-Thr-Thr-Asp-His-Gln-Met-Ala-Arg-Lys-Cys-Asp-Asp-Cys-Cys-Gly-Gly-Lys-Gly-Arg-Gly-Lys-Cys-Tyr-Gly-Pro-Gln-Cys-Leu-Cys-Arg-NH2 (Reported disulfide bonds between Cys2-Cys19, Cys5-Cys28, Cys16-Cys33, and Cys20-Cys35) <strong>Amount:</strong> 500 ug <strong>Molecular Weight:</strong> 3995.6 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Wang D, Starr R, Chang WC, Aguilar B, Alizadeh D, Wright SL, Yang X, Brito A, Sarkissian A, Ostberg JR, Li L, Shi Y, Gutova M, Aboody K, Badie B, Forman SJ, Barish ME, Brown CE. Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma Sci Transl Med. 2020 Mar 4;12(533):eaaw2672. 2: The MICAD Research Team. Chlorotoxin:Cy5.5 2007 Jul 23 [updated 2007 Aug 30]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 3: Dardevet L, Rani D, Aziz TA, Bazin I, Sabatier JM, Fadl M, Brambilla E, De Waard M. Chlorotoxin: a helpful natural scorpion peptide to diagnose glioma and fight tumor invasion Toxins (Basel). 2015 Mar 27;7(4):1079-101. 4: Cohen G, Burks SR, Frank JA. Chlorotoxin-A Multimodal Imaging Platform for Targeting Glioma Tumors Toxins (Basel). 2018 Nov 26;10(12):496. 5: Ojeda PG, Wang CK, Craik DJ. Chlorotoxin: Structure, activity, and potential uses in cancer therapy Biopolymers. 2016 Jan;106(1):25-36. 6: The MICAD Research Team. (131)I-Chlorotoxin 2007 Jul 17 [updated 2007 Aug 8]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 7: Fu Y, An N, Li K, Zheng Y, Liang A. Chlorotoxin-conjugated nanoparticles as potential glioma-targeted drugs J Neurooncol. 2012 May;107(3):457-62. 8: Zhao L, Shi X, Zhao J. Chlorotoxin-conjugated nanoparticles for targeted imaging and therapy of glioma Curr Top Med Chem. 2015;15(13):1196-208. 9: Cohen-Inbar O, Zaaroor M. Glioblastoma multiforme targeted therapy: The Chlorotoxin story J Clin Neurosci. 2016 Nov;33:52-58. <a href="https://pubmed.ncbi.nlm.nih.gov/36559106">10: Shrestha A, Lahooti B, Mikelis CM, Mattheolabakis G. Chlorotoxin and Lung Cancer: A Targeting Perspective for Drug Delivery Pharmaceutics. 2022 Nov 26;14(12):2613. </a> <br><strong>Products Related to Chlorotoxin can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>