Brain Natriuretic Peptide (1-32), rat (acetate)

Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes) [1].

Product Specifications

Product Name Alternative

BNP (1-32), rat (acetate)

UNSPSC

12352209

Target

Angiotensin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/brain-natriuretic-peptide-1-32-rat-acetate.html

Purity

98.66

Solubility

H2O

Smiles

O=C([C@H](CSSC[C@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@](NC([C@@H](NC([C@@H](NC([C@](NC([C@@H](NC([C@@H](NC(CNC1=O)=O)CCC(N)=O)=O)CCCCN)=O)([H])[C@@H](C)CC)=O)CC(O)=O)=O)CCCNC(N)=N)=O)([H])[C@@H](C)CC)=O)=O)C)=O)C(C)C)=O)CO)=O)CCCNC(N)=N)=O)CC(C)C)=O)=O)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)NC([C@H](CO)NC([C@H](CO)NC([C@H](CO)NC([C@@H](NC([C@H](C)NC([C@H](CCSC)NC([C@H](CCCCN)NC([C@H](CO)NC([C@@H](N)CC(N)=O)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)N[C@H]1CC4=CC=CC=C4.CC(O)=O

Molecular Formula

C148H243N47O46S3

Molecular Weight

3512.99

References & Citations

[1]Dickey DM, et al. Human B-type natriuretic peptide is not degraded by meprin A. Biochem Pharmacol. 2010 Oct 1;80 (7) :1007-11.|[2]Wellard J, et al. Natriuretic peptides, but not nitric oxide donors, elevate levels of cytosolic guanosine 3',5'-cyclic monophosphate in ependymal cells ex vivo. Neurosci Lett. 2006 Jan 16;392 (3) :187-92.|[3]Seymour AA, et al. Potentiation of brain natriuretic peptides by SQ 28,603, an inhibitor of neutral endopeptidase3.4.24.11, in monkeys and rats. J Pharmacol Exp Ther. 1992 Jul;262 (1) :60-70.