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Anti-MRSA agent 13

Anti-MRSA agent 13 (Compound 9b) is an agent against methicillin-resistant Staphylococcus aureus (MRSA), exhibiting a minimum inhibitory concentration (MIC) of 0.5–2 μg/mL against clinically isolated MRSA strains. Anti-MRSA agent 13 possesses favorable biosafety, plasma tolerance stability, and a low tendency to develop resistance. Anti-MRSA agent 13 disrupts cell walls and membranes, reduces metabolic activity, causes oxidative damage, affects DNA function, and ultimately leads to MRSA death through multi-target synergies[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/anti-mrsa-agent-13.html

Smiles

CC1=[N+](C)C=CC2=C1N(CCCCCCCCN3C4=C(C=CC=C4)C5=C3C(C)=[N+](C)C=C5)C6=CC=CC=C62.[I-].[I-]

Molecular Formula

C34H40I2N4

Molecular Weight

758.52

References & Citations

[1]Liu J, et al. Quaternized antimicrobial peptide mimics based on harmane as potent anti-MRSA agents by multi-target mechanism covering cell wall, cell membrane and intracellular targets[J]. European Journal of Medicinal Chemistry, 2024: 116657.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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