Purified Anti-Human CD19 Antibody[4G7]
Product Specifications
Background
CD19 protein is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses . CD19 is expressed throughout B cell development from pre-B cells through mature B cells, and it is commonly used as a B cell lineage marker . It is required for the responsiveness of mature B cell to antigen stimulation, germinal center development, and antibody affinity maturation . The CD19 protein associates with the B cell antigen receptor (BCR), CD81, CD38, CD21, CD22, and IFITM1/CD225/Leu13. These associations enable CD19 to amplify B cell signaling and reduce the threshold for antigen stimulation through the BCR.
Abbreviation
CD19
Gene ID
930
UniProt
P15391
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD19 protein
Target
CVID; B-lymphocyteantigenCD; B-lymphocyte antigen CD; T-cellsurfaceantigenLeu; Differentiation antigen CD; T-cell surface antigen Leu; B-lymphocytesurfaceantigenB; B-lymphocyte surface antigen B; B4; CVID3; CD19; B-lymphocyteantigenCD19; B-lymphocytesurfaceantigenB4; T-cellsurfaceantigenLeu-12; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12; B4; CVID3; CD19; CD19 molecule
Clonality
Monoclonal
Clone
4G7
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Stem Cells
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/ds48pd
Product MSDS
https://789.bio/eb/5liSdS
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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