3-Methylsalicylic acid

3-Methylsalicylic acid (o-Cresotic acid) is a derivative of salicylic acid. 3-Methylsalicylic acid exhibits significant fibrinolytic activity in human plasma by activating the fibrinolytic system. 3-Methylsalicylic acid can be used as an intermediate for the synthesis of other compounds. 3-Methylsalicylic acid inhibits the feeding of midges[1][2].

Product Specifications

CAS Number

[83-40-9]

Product Name Alternative

O-Cresotic acid; Hydroxytoluic acid

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/3-Methylsalicylic-acid.html

Purity

99.63

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)C1=CC=CC(C)=C1O

Molecular Formula

C8H8O3

Molecular Weight

152.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Chae HD, et al. SAR optimization studies on modified salicylamides as a potential treatment for acute myeloid leukemia through inhibition of the CREB pathway. Bioorg Med Chem Lett. 2019 Aug 15;29 (16) :2307-2315.|[2]Stuart AE, et al. Repellent and antifeedant activity of salicylic acid and related compounds against the biting midge, Culicoides impunctatus (Diptera: Ceratopogonidae) . J Med Entomol. 2000 Mar;37 (2) :222-7.