Breviscapine

Breviscapine is a crude flavonoid extract of Breviscapine, which is more than 85% of the active ingredient, Breviscapine. Breviscapine has a wide range of cardiovascular pharmacological activities, such as increasing blood flow, improving microcirculation, dilating blood vessels, reducing blood viscosity, promoting fibrinolysis, inhibiting platelet aggregation and thrombosis. Breviscapine has been used in the study of cerebral infarction and its sequelae, cerebral thrombosis, coronary heart disease and angina pectoris[1][2].

Product Specifications

CAS Number

[116122-36-2]

Product Name Alternative

Breviscapinun

UNSPSC

12352005

Target

Interleukin Related; NF-κB

Type

Natural Products

Related Pathways

Immunology/Inflammation; NF-κB

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/breviscapine.html

Purity

95.59

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3C(O)=O)=C4O)C2=C4O.O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O5)O)O)[C@@H]5OC6=CC(O)=C7C(C=C(C8=CC=C(O)C=C8)OC7=C6)=O

Molecular Weight

1293.34

References & Citations

[1]Gao J, et al. Therapeutic Effects of Breviscapine in Cardiovascular Diseases: A Review. Front Pharmacol. 2017 May 23;8:289. |[2]Wen L, et al. Breviscapine: A Review on its Phytochemistry, Pharmacokinetics and Therapeutic Effects. Am J Chin Med. 2021;49 (6) :1369-1397.