KDU731
KDU731, an orally active C. parvum PI4K inhibitor with an IC50 value of 25 nM, blocks Cryptosporidium infection in vitro and in vivo[1][2]. KDU731 is a promising agent candidate for the treatment of diarrhea caused by Cryptosporidium and meets a broad range of safety[2].
Product Specifications
CAS Number
[1610610-48-4]
UNSPSC
12352005
Target
Parasite; PI4K
Type
Reference compound
Related Pathways
Anti-infection; PI3K/Akt/mTOR
Applications
Neuroscience-Neuromodulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/kdu731.html
Purity
99.52
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
O=C(C1=CC2=C(C3=CC=C(C(N)=O)C=C3)C=NN2C=C1)N(C)C4=NC=C(C#N)C=C4
Molecular Formula
C22H16N6O2
Molecular Weight
396.40
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-103583/KDU731-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-103583/KDU731-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI4K
Available Sizes
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