UAP56 Recombinant Rabbit Monoclonal Antibody [JE34-73]
Spliceosome RNA helicase BAT1 is an enzyme that in humans is encoded by the BAT1 gene. This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
DDX39B, BAT1, UAP56
Swiss Prot
Q13838 Human, Q9Z1N5 Mouse, Q63413 Rat
Cellular Locus
Nucleus, Nucleus speckle, Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within
Isotype
IgG
Clone
JE34-73
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC, IF-Tissue
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:1,000-1:10,000 ;IF-Cell: 1:100 ;FC: 1:1,000 ;IF-Tissue: 1:200-1:5,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 49 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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