Zoliprofen
Zoliprofen (480156-S), a new non-steroidal anti-inflammatory agent, has potent pain suppressing effect. Zoliprofen has strong antagonistic action against bradykinin, markedly inhibiting all bradykinin-induced edema and pain reactions. Zoliprofen weakly inhibits Arachidonic acid -induced edema and pain reactions but also inhibits PGE2 synthesis of bovine vesicular gland microsomes[1].
Product Specifications
CAS Number
56355-17-0
Product Name Alternative
480156-S
UNSPSC
12352005
Target
Bradykinin Receptor; Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/zoliprofen.html
Smiles
O=C(O)C(C)C1=CC=C(OC2=NC=CS2)C=C1
Molecular Formula
C12H11NO3S
Molecular Weight
249.29
References & Citations
[1]K Hirose, et al. Pharmacological properties of 2-[4- (2-thiazolyloxy) -phenyl]-propionic acid (480156-S), a new non-steroidal antiinflammatory agent. Arzneimittelforschung. 1984;34 (3) :280-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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