Gol-NTR

Gol-NTR is a Golgi-targetable probe with high selectivity and sensitivity. Gol-NTR is Nitroreductase (NTR) -activated and has visualization acute lung injury (ALI) and repair function. Gol-NTR has a low detection limit of 54.8 ng/mL. Gol-NTR can be used for the research for monitoring and assessing research response of sepsis-induced ALI[1].

Product Specifications

CAS Number

[2968461-58-5]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/gol-ntr.html

Purity

99.44

Solubility

10 mM in DMSO

Smiles

FC(F)(C1=NC(C=C(NC(OCC2=CC=C([N+]([O-])=O)C=C2)=O)C=C3)=C3C(C4=CC=CC=C4)=C1)F

Molecular Formula

C24H16F3N3O4

Molecular Weight

467.40

References & Citations

[1]Tang Z, et al. Precise Monitoring and Assessing Treatment Response of Sepsis-Induced Acute Lung Hypoxia with a Nitroreductase-Activated Golgi-Targetable Fluorescent Probe. Anal Chem. 2022 Oct 25;94 (42) :14778-14784.