Nintedanib esylate (Standard)
Nintedanib esylate (Standard) is the analytical standard of Nintedanib esylate. This product is intended for research and analytical applications. Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.
Product Specifications
CAS Number
[656247-18-6]
Product Name Alternative
BIBF 1120 (esylate) (Standard)
UNSPSC
12352005
Hazard Statement
H360-H372-H411
Target
FGFR; PDGFR; Reference Standards; VEGFR
Type
Reference Standards
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nintedanib-esylate-standard.html
Smiles
O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(N(C)C(CN4CCN(C)CC4)=O)C=C3)/C5=CC=CC=C5)OC.CCS(=O)(O)=O
Molecular Formula
C33H39N5O7S
Molecular Weight
649.76
Precautions
P260-P264-P270-P273-P280-P391-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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