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SI-2 (hydrochloride)

SI-2 (EPH 116 hydrochloride) is a highly promising SRC-3 inhibitor (PPI) . SI-2 (EPH 116 hydrochloride) has a much improved toxicity and pharmacokinetic profile, with acceptable oral availability[1].

Product Specifications

CAS Number

[1992052-49-9]

Product Name Alternative

EPH 116 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/si-2-hydrochloride.html

Purity

98.06

Solubility

DMSO : 5 mg/mL (ultrasonic)

Smiles

CN1C(N/N=C(C)/C2=CC=CC=N2)=NC3=CC=CC=C13.Cl

Molecular Formula

C15H16ClN5

Molecular Weight

301.77

Precautions

H302, H315, H319

References & Citations

[1]Song X, et al. Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3. Proc Natl Acad Sci U S A. 2016 May 3;113 (18) :4970-5.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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