MAX-10181

MAX-10181 (PD-1/PD-L1-IN-30) is a PD-1/PD-L1 binding inhibitor, with an IC50 value of 0.018 μM. MAX-10181 can be used for research of cancers and other related diseases[1].

Product Specifications

CAS Number

[2171558-14-6]

Product Name Alternative

PD-1/PD-L1-IN-30

UNSPSC

12352005

Target

PD-1/PD-L1

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/max-10181.html

Concentration

10mM

Purity

98.56

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=C(C=CC=C1/C=C/C2=C(C=CC(CNC(CO)(C)C(O)=O)=C2)C(F)(F)F)C3=CC=C(OCCO4)C4=C3

Molecular Formula

C29H28F3NO5

Molecular Weight

527.53

References & Citations

[1]Wang, Yuguang, et al. Aromatic acetylene or aromatic ethylene compound, intermediate, preparation method, pharmaceutical composition and use thereof. Patent. WO2018006795.