Sofalcone
Sofalcone, a gastric antiulcer agent, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.
Product Specifications
CAS Number
64506-49-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; Bacterial
Type
Reference compound
Related Pathways
Anti-infection; Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Sofalcone.html
Purity
99.01
Solubility
DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL
Smiles
O=C(O)COC1=CC(OC/C=C(C)/C)=CC=C1C(/C=C/C2=CC=C(OC/C=C(C)/C)C=C2)=O
Molecular Formula
C27H30O6
Molecular Weight
450.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Onda K, et al. Sofalcone upregulates the nuclear factor (erythroid-derived 2) -like 2/heme oxygenase-1 pathway, reduces soluble fms-like tyrosine kinase-1, and quenches endothelial dysfunction: potential therapeutic for preeclampsia. Hypertension. 2015 Apr;65 (4) :855-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
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