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THP-1/MV-4-11 against-1

THP-1/MV-4-11 against-1 (compound 12k) is an anticancer agent with potency inhibitory against THP-1/MV/4 cells (IC50=29 nM and 98 nM, respectively) . THP-1/MV-4-11 against-1 is one of 5-substituted thiazolyl urea derivatives, can be used in leukemic diseases research[1].

Product Specifications

CAS Number

[2978623-53-7]

UNSPSC

12352005

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/thp-1-mv-4-11-against-1.html

Smiles

O=C(N1CCN(CC1)C2=CC=C(C=C2)Cl)NC3=NC=C(CC4=CC=C(C=C4)OC)S3

Molecular Formula

C22H23ClN4O2S

Molecular Weight

442.96

References & Citations

[1]Peng C, et al. The synthesis and antileukemic activity of 5-substituted thiazolyl urea derivatives. Bioorg Med Chem Lett. 2025 Jan 1;115:130018.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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