THP-1/MV-4-11 against-1
THP-1/MV-4-11 against-1 (compound 12k) is an anticancer agent with potency inhibitory against THP-1/MV/4 cells (IC50=29 nM and 98 nM, respectively) . THP-1/MV-4-11 against-1 is one of 5-substituted thiazolyl urea derivatives, can be used in leukemic diseases research[1].
Product Specifications
CAS Number
[2978623-53-7]
UNSPSC
12352005
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thp-1-mv-4-11-against-1.html
Smiles
O=C(N1CCN(CC1)C2=CC=C(C=C2)Cl)NC3=NC=C(CC4=CC=C(C=C4)OC)S3
Molecular Formula
C22H23ClN4O2S
Molecular Weight
442.96
References & Citations
[1]Peng C, et al. The synthesis and antileukemic activity of 5-substituted thiazolyl urea derivatives. Bioorg Med Chem Lett. 2025 Jan 1;115:130018.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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