Galectin-8/LGALS8, Rat (His)

Galectin-8 belongs to the family of animal lectins that bind to different glycoconjugates. Galectin-8 inhibits MTOR and AMPK signaling pathways to induce autophagy in response to lysosomal damage. Galectin-8 is highly expressed in a variety of tumors. Galectin-8 Protein, Rat (His) is the recombinant rat-derived Galectin-8, expressed by E. coli, with N-6*His labeled tag. The total length of Galectin-8 Protein, Rat (His) is 316 a.a..

Product Specifications

Product Name Alternative

Galectin-8/LGALS8 Protein, Rat (His), Rat, E. coli

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/galectin-8-protein-rat-his.html

Purity

97.00

Smiles

MLSLSNLQNIIYNPTIPYVSTITEQLKPGSLIVIRGHVPKDSERFQVDFQHGNSLKPRADVAFHFNPRFKRSNCIVCNTLTNEKWGWEEITHDMPFRKEKSFEIVIMVLKNKFQVAVNGKHILLYAHRINPEKIDTLGIYGKVNIHSIGFRFSSDLQSMETSTLGLTQISKENIQKSGKLHLSLPFEARLNASMGPGRTVVVKGEVNTNAKSFNVDLVAGRSRDIALHLNPRLNVKAFVRNSFLQDAWGEEERNITCFPFSSGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKDLSSIDTLAVDGDIRLLDVRSW

Molecular Formula

116641 (Gene_ID) Q6IN24 (M1-W316) (Accession)

Molecular Weight

Approximately 34 kDa

References & Citations

[1]Zick Y. Galectin-8, cytokines, and the storm. Biochem Soc Trans. 2022 Feb 28;50 (1) :135-149.|[2]Storti P, et al. Role of Galectins in Multiple Myeloma. Int J Mol Sci. 2017 Dec 17;18 (12) :2740.|[3]Jia J, et al. Galectins control MTOR and AMPK in response to lysosomal damage to induce autophagy. Autophagy. 2019 Jan;15 (1) :169-171.