Meldonium (dihydrate)
Meldonium (MET-88) dihydrate functions as a cardioprotective agent by cpmpetetively inhibiting γ-butyrobetaine hydroxylase (BBOX) and carnitine/organic cation transporter type 2 (OCTN2) . Mildronate dihydrate exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Meldonium dihydrate is a fatty acid oxidation inhibitor[1][2].
Product Specifications
CAS Number
86426-17-7
Product Name Alternative
MET-88 (dihydrate) ; Quaterin (dihydrate)
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/meldonium-dihydrate.html
Purity
99.0
Solubility
DMSO : 4.85 mg/mL (ultrasonic; warming; adjust pH to 4 with HCl; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)
Smiles
C[N+](C)(C)NCCC([O-])=O.O.O
Molecular Formula
C6H18N2O4
Molecular Weight
182.22
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
J Pharm Biomed Anal. 2021 Feb 20:195:113870.|J Anim Sci. 2022 Apr 1;100 (4) :skac069.|Nat Commun. 2025 Feb 11;16 (1) :1543.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![APC Anti-Human CD83 Antibody[HB15e]](https://cdn.genprice.uk/products/763/68dd14a5061270361e7d15b0/imageurl/e-ab-f0993e.webp)