Protocatechualdehyde

Protocatechualdehyde (Catechaldehyde), a natural polyphenol compound isolated from the roots of radix Salviae Miltiorrhizae, is associated with a wide variety of biological activities and has been widely used in medicine as an antioxidant, anti-aging, an antibacterial and anti-inflammatory agent[1].

Product Specifications

CAS Number

[139-85-5]

Product Name Alternative

Catechaldehyde; Protocatechuic aldehyde; Rancinamycin IV

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Bacterial; Endogenous Metabolite; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/Protocatechualdehyde.html

Purity

99.98

Solubility

DMSO : ≥ 50 mg/mL

Smiles

O=CC1=CC=C(O)C(O)=C1

Molecular Formula

C7H6O3

Molecular Weight

138.12

Precautions

H315, H319, H335

References & Citations

[1]Li S, et al. Evaluation of the Antibacterial Effects and Mechanism of Action of Protocatechualdehyde against Ralstonia solanacearum. Molecules. 2016 Jun 9;21 (6) .|[2]Choi J, et al. Anticancer activity of protocatechualdehyde in human breast cancer cells. J Med Food. 2014 Aug;17 (8) :842-8.|[3]Jeong JB, et al. Protocatechualdehyde possesses anti-cancer activity through downregulating cyclin D1 and HDAC2 in human colorectal cancer cells. Biochem Biophys Res Commun. 2013 Jan 4;430 (1) :381-6.