Ulocuplumab
Ulocuplumab (Anti-Human CXCR4 Recombinant Antibody/BMS-936564/MDX1338) is a fully human IgG4 anti-CXCR4 antibody. Ulocuplumab induces apoptosis and inhibits CXCL12 mediated CXCR4 activation-migration of chronic lymphocytic leukemia (CLL) . Ulocuplumab exhibits antitumor activity in established tumors including acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL), and multiple myeloma xenograft models[1][2].
Product Specifications
CAS Number
1375830-34-4
Product Name Alternative
BMS 936564; MDX 1338; Anti-Human CXCR4 Recombinant Antibody
UNSPSC
12352203
Target
CXCR
Type
Inhibitory Antibodies
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ulocuplumab.html
Purity
99.90
Solubility
10 mM in DMSO
Smiles
[Ulocuplumab]
Molecular Weight
(144.84 kDa)
References & Citations
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3
Isoform
CXCR4
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Porcine CGG triplet repeat-binding protein 1 (CGGBP1) ELISA Kit
Porcine CGG triplet repeat-binding protein 1 (CGGBP1) ELISA Kit
Porcine CGG triplet repeat-binding protein 1 (CGGBP1) ELISA Kit