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Myosin modulator 2

Myosin modulator 2 (Compound B172) is a modulator for myosin, that inhibits ATPase in rabbits psoas, porcine atria and in porcine ventricle, with IC25s of 2.013, 2.94 and 20.93 μM, respectively. Myosin modulator 2 regulates systolic cardiac performance in Sprague Dawley rats[1].

Product Specifications

CAS Number

3034189-87-9

UNSPSC

12352005

Target

Myosin

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/myosin-modulator-2.html

Solubility

10 mM in DMSO

Smiles

O=C1NC2=CC=C(F)C=C2CN1CC(N[C@H](C3=NC=C(C#N)C=C3)C)=O

Molecular Formula

C18H16FN5O2

Molecular Weight

353.35

References & Citations

[1]Hawryluk N, et al., 1,4-dihydroquinazolinone compounds and uses thereof. WO2024073426A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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