Myosin modulator 2
Myosin modulator 2 (Compound B172) is a modulator for myosin, that inhibits ATPase in rabbits psoas, porcine atria and in porcine ventricle, with IC25s of 2.013, 2.94 and 20.93 μM, respectively. Myosin modulator 2 regulates systolic cardiac performance in Sprague Dawley rats[1].
Product Specifications
CAS Number
3034189-87-9
UNSPSC
12352005
Target
Myosin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/myosin-modulator-2.html
Solubility
10 mM in DMSO
Smiles
O=C1NC2=CC=C(F)C=C2CN1CC(N[C@H](C3=NC=C(C#N)C=C3)C)=O
Molecular Formula
C18H16FN5O2
Molecular Weight
353.35
References & Citations
[1]Hawryluk N, et al., 1,4-dihydroquinazolinone compounds and uses thereof. WO2024073426A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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