DDR Inhibitor
DDR Inhibitor is a potent discoidin domain receptor (DDR) inhibitor, with an IC50 of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM.
Product Specifications
CAS Number
[1644069-80-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Discoidin Domain Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/DDR_Inhibitor.html
Purity
99.43
Solubility
DMSO : 65 mg/mL (ultrasonic)
Smiles
O=C(C1=CN=C2C=CC=CN21)NC3=CC(CNC(NC4=CC=CC(F)=C4)=O)=CC=C3C
Molecular Formula
C23H20FN5O2
Molecular Weight
417.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Gordon Saxty, et al. Imidazo-condensed bicycles as inhibitors of discoidin domain receptors (ddrs)
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1308503-01 0.02 mg (E-Coli)
Recombinant Humulus lupulus Adenylate isopentenyltransferase
Ask
View Details MBS1308503-02 0.02 mg (Yeast)
Recombinant Humulus lupulus Adenylate isopentenyltransferase
Ask
View Details MBS1308503-03 0.1 mg (E-Coli)
Recombinant Humulus lupulus Adenylate isopentenyltransferase
Ask
View Details MBS1308503-04 0.1 mg (Yeast)
Recombinant Humulus lupulus Adenylate isopentenyltransferase
Ask
View Details MBS1308503-05 0.02 mg (Baculovirus)
Recombinant Humulus lupulus Adenylate isopentenyltransferase
Ask
View Details MBS1308503-06 0.02 mg (Mammalian-Cell)
Recombinant Humulus lupulus Adenylate isopentenyltransferase
Ask
View Details