Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Demecarium Bromide

Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor, with an apparent affinity (Kiapp) of 0.15 μM[1]. Demecarium Bromide (BC-48) is used as a glaucoma agent[2].

Product Specifications

CAS Number

[56-94-0]

Product Name Alternative

BC-48

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Demecarium_Bromide.html

Purity

95.0

Solubility

DMSO : 160 mg/mL (ultrasonic)

Smiles

O=C(N(CCCCCCCCCCN(C(OC1=CC([N+](C)(C)C)=CC=C1)=O)C)C)OC2=CC([N+](C)(C)C)=CC=C2.[Br-].[Br-]

Molecular Formula

C32H52Br2N4O4

Molecular Weight

716.59

Precautions

H302, H315, H319, H335

References & Citations

[1]Brown JH, et al. Activation and blockade of cardiac muscarinic receptors by endogenous acetylcholine and cholinesterase inhibitors. J Pharmacol Exp Ther. 1982 Oct;223 (1) :20-4.|[2]Gum GG, et al. Effect of topically applied demecarium bromide and echothiophate iodide on intraocular pressure and pupil size in beagles with normotensive eyes and beagles with inherited glaucoma. Am J Vet Res. 1993 Feb;54 (2) :287-93.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-B1626A/Demecarium-Bromide-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-B1626A/Demecarium-Bromide-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Recombinant Brucella abortus Thiazole synthase (thiG)
MBS1006683-01 0.02 mg (E-Coli)

Recombinant Brucella abortus Thiazole synthase (thiG)

Ask
View Details
Recombinant Brucella abortus Thiazole synthase (thiG)
MBS1006683-02 0.1 mg (E-Coli)

Recombinant Brucella abortus Thiazole synthase (thiG)

Ask
View Details
Recombinant Brucella abortus Thiazole synthase (thiG)
MBS1006683-03 0.02 mg (Yeast)

Recombinant Brucella abortus Thiazole synthase (thiG)

Ask
View Details
Recombinant Brucella abortus Thiazole synthase (thiG)
MBS1006683-04 0.1 mg (Yeast)

Recombinant Brucella abortus Thiazole synthase (thiG)

Ask
View Details
Recombinant Brucella abortus Thiazole synthase (thiG)
MBS1006683-05 0.02 mg (Baculovirus)

Recombinant Brucella abortus Thiazole synthase (thiG)

Ask
View Details
Recombinant Brucella abortus Thiazole synthase (thiG)
MBS1006683-06 0.02 mg (Mammalian-Cell)

Recombinant Brucella abortus Thiazole synthase (thiG)

Ask
View Details