Y13g (dihydrochloride)
Product Specifications
Product Name Alternative
SHP-141
UNSPSC Description
Y13g dihydrochloride is the potent inhibitor of both AChE and IL-6. Interleukin-6 (IL-6) and acetylcholinesterase (AChE) are two important targets implicated in progression of Alzheimer's Disease (AD). Y13g dihydrochloride reverses the STZ (HY-13753)-induced memory deficit, and shows histopathology similarly as in normal animals[1].
Target Antigen
Cholinesterase (ChE); Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/y13g-dihydrochloride.html
Purity
99.89
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
COC1=CC(O)=C(C(OC)=C1)C(CCCN2CCNCC2)=O.[H]Cl.[H]Cl
Molecular Weight
381.29
References & Citations
[1]Kaur S, et al. Design, molecular Docking, synthesis and evaluation of xanthoxylin hybrids as dual inhibitors of IL-6 and acetylcholinesterase for Alzheimer's disease. Bioorg Chem. 2022;121:105670.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-115910A/Y13g-dihydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-115910A/Y13g-dihydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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