7α,15-Dihydroxydehydroabietic acid

7α,15-Dihydroxydehydroabietic acid is a natural abietane-type diterpenoid with antiangiogenic effects[1].

Product Specifications

CAS Number

[155205-64-4]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H332-H335

Target

ERK

Type

Natural Products

Related Pathways

MAPK/ERK Pathway; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/7α-15-dihydroxydehydroabietic-acid.html

Solubility

10 mM in DMSO

Smiles

O=C([C@]1(C)CCC[C@]2(C)C3=C([C@H](O)C[C@@]12[H])C=C(C(C)(O)C)C=C3)O

Molecular Formula

C20H28O4

Molecular Weight

332.43

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Tae Kyoung Lee, et al. 7α,15-Dihydroxydehydroabietic acid from Pinus koraiensis inhibits the promotion of angiogenesis through downregulation of VEGF, p-Akt and p-ERK in HUVECs. Bioorg Med Chem Lett. 2018 Apr 1;28 (6) :1084-1089.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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