Prodigiosin

Prodigiosin (Prodigiosine) is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin is a potent inhibitor of the Wnt/β-catenin pathway. Prodigiosin has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties[1][2].

Product Specifications

CAS Number

[82-89-3]

Product Name Alternative

Prodigiosine; NSC47147

UNSPSC

12352005

Target

Apoptosis; Bacterial; Fungal; Parasite; Wnt

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/prodigiosin.html

Purity

99.89

Solubility

DMSO : ≥ 25 mg/mL

Smiles

CCCCCC1=C/C(N=C1C)=C\C2=C(OC)C=C(C3=CC=CN3)N2

Molecular Formula

C20H25N3O

Molecular Weight

323.43

References & Citations

[1]Woodhams DC, et al. Prodigiosin, Violacein, and Volatile Organic Compounds Produced by Widespread Cutaneous Bacteria of Amphibians Can Inhibit Two Batrachochytrium Fungal Pathogens. Microb Ecol. 2018 May;75 (4) :1049-1062.|[2]Wang Z, et al. Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells. Proc Natl Acad Sci U S A. 2016 Nov 15;113 (46) :13150-13155.