Antisauvagine-30
Antisauvagine-30 (aSvg-30) is a potent, competitive and selective CRF2 receptor antagonist with Kd values of 1.4 nM and 153.6 nM for mouse CRF2β and rat CRF1 receptors, respectively[1].
Product Specifications
CAS Number
[220673-95-0]
Product Name Alternative
ASvg-30
UNSPSC
12352211
Target
CRFR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/antisauvagine-30.html
Purity
99.74
Solubility
DMSO : 4 mg/mL (ultrasonic)
Smiles
[(D-Phe)-HLLRKMIEIEKQEKEKQQAANNRLLLDTI-NH2]
Molecular Formula
C161H274N48O46S
Molecular Weight
3650.26
References & Citations
[1]O Brauns, et al. Pharmacological and chemical properties of astressin, antisauvagine-30 and alpha-helCRF: significance for behavioral experiments. Neuropharmacology. 2001 Sep;41 (4) :507-16.|[2]Farahnaz Sananbenesi, et al. Mitogen-activated protein kinase signaling in the hippocampus and its modulation by corticotropin-releasing factor receptor 2: a possible link between stress and fear memory. J Neurosci
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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