Almitrine mesylate

Almitrine mesylate, a peripheral chemoreceptor agonist, inhibits selectively the Ca2+-dependent K+ channel.

Product Specifications

CAS Number

[29608-49-9]

Product Name Alternative

Almitrine bismesylate; Almitrine bismethanesulfonate; Almitrine dimesylate

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Almitrine_mesylate.html

Concentration

10mM

Purity

99.81

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C=CCNC1=NC(N(CC2)CCN2C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)=NC(NCC=C)=N1.O=S(O)(C)=O.O=S(O)(C)=O

Molecular Formula

C28H37F2N7O6S2

Molecular Weight

669.76

Precautions

H302, H315, H319, H335

References & Citations

[1]López-López JR, et al. Effects of Almitrine bismesylate on the ionic currents of chemoreceptor cells from the carotid body. Mol Pharmacol. 1998 Feb;53 (2) :330-9.|[2]Bee D, et al. An analysis of the action of an analogue of Almitrine bismesylate in the rat model of hypoxic lung disease. Exp Physiol. 1992 Nov;77 (6) :819-28.