What is the catalog number for ZIP4H?

The catalog number for ZIP4H is 103-M565.

What sizes are available for ZIP4H?

ZIP4H is available in the following size(s): 50 µg.

ZIP4H is currently made to order / not held in immediate stock. Contact us for lead time.

ZIP4H

ZIP4 homolog (ZIP4H), also known as testis expressed sequence 11 (Tex11) is a 947 amino acid (aa) X chromosome-encoded protein that is selectively expressed in primordial male germ cells. It associates with Nbs1 of the Mre11 protein complex which results in localization to areas of synaptonemal contact between meiotic chromosomes. During meiosis, ZIP4H promotes sister chromatid synapsis and crossover in response to programmed double stranded DNA breaks. ZIP4H deficiency leads to increased spermatocyte apoptosis and male sterility. Alternate splicing in mouse generates an additional isoform with a substitution (aa 691‑707) and truncation (aa 708‑947) at the C-terminus. Within aa 768‑947, mouse ZIP4H shares 44% and 73% aa sequence identity with human and rat ZIP4H, respectively.

Product Specifications

Synonyms

Testis expressed 11, testis expressed sequence 11, testis-expressed sequence 11 protein, Tex11, TGC1, TSGA3, ZIP4H

NCBI Gene ID

83558

UniProt

Q14AT2

Accession Number

NP_113561.2

Accession Number mRNA

NM_031384.2

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Recombinant Mouse ZIP4H

Clone

(#5E34)

Applications

WB

Purification Method

Protein G/A chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.