VWF-A2
Human vWF is a serum glycoprotein that mediates platelet adhesion to injured vascular endothelium. vWF function is regulated by ADAMTS13 mediated proteolysis within the A2 domain. Mutations of this protease cause thrombotic thrombocytopenic purpura.
Product Specifications
Synonyms
VWF; VWD; F8VWF
NCBI Gene ID
7450
UniProt
P04275
Accession Number
NP_000543.2
Accession Number mRNA
NM_000552.3
Chromosomal Location
12p13.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant vWF-A2
Clone
(#5F22)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Bioactivity
WB: 1:250-500
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2
Curated Selection
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