Viral-MIP-2
VMIP-2 is a chemokine analog encoded by human herpes virus, and has been shown to have antagonist activity towards several chemokine receptors. Recombinant vMIP-2 is a 7.9 kDa protein consisting of 70 amino acids including the four highly conserved cysteine residues present in CC chemokines.
Product Specifications
Synonyms
CXCL2; GRO2; GROb; MIP2; MIP2A; SCYB2; MGSA-b; MIP-2a; CINC-2a
NCBI Gene ID
2920
UniProt
Q98157
Accession Number
YP_001129362.1
Accession Number mRNA
NC_009333.1
Chromosomal Location
4q21
Reactivity
Human
Cross Reactivity
Human, Mouse
Target Antigen
Ant human Vinculin
Sequence
LGASWHRPDK CCLGYQKRPL PQVLLSSWYP TSQLCSKPGV IFLTKRGRQV CADKSKDWVK KLMQQLPVTA
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by the inhibitory effect on monocyte migration response to human MIP-1 alpha using a concentration range of 1.0µg-10.0µg/ml of viral MIP-2 will inhibit 25ng/ml of human MIP-1 alpha.
Length
70
Form
Lyophilized
Molecular Weight
7.9 kDa
Host or Source
E. coli
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