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VCAM-1

VCAM-1 is expressed on the surface of activated endothelial cells and macrophages. It binds to leukocyte integrins VLA-4 and alpha 4 beta 7 to promote leukocyte adhesion at sites of inflamed vasculature.

Product Specifications

Synonyms

VCAM1; CD106; INCAM-100

NCBI Gene ID

7412

UniProt

P19320

Accession Number

NP_542413.1

Accession Number mRNA

NM_080682.2

Chromosomal Location

1p32-p31

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

LPS activated HUVECs

Clone

(#6C12)

Applications

WB, IHC (P)

Purification Method

Protein G chromatography

Assay Protocol

Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Bioactivity

WB: 1:100-1000; IHC (Formalin/Paraffin) : 1:50-200

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

Host or Source

Mouse

Isotype

IgG1

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