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UPA

U-Plasminogen Activator (uPA) is a serine protease that converts plasminogen to plasmin, with roles in a variety of normal and pathological processes that include cell migration and tissue destruction. uPA is a potent marker of invasion and metastasis in a variety of human cancers including breast, stomach, colon, bladder, ovarian, brain, and endometrium.

Product Specifications

Synonyms

PLAU; ATF; QPD; UPA; URK; u-PA; BDPLT5

NCBI Gene ID

5328

UniProt

P00749

Accession Number

NP_002649.1

Accession Number mRNA

NM_002658.3

Chromosomal Location

10q24

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human uPA

Clone

(#8G26)

Applications

WB

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Host or Source

Mouse

Isotype

IgG2

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