UPA
U-Plasminogen Activator (uPA) is a serine protease that converts plasminogen to plasmin, with roles in a variety of normal and pathological processes that include cell migration and tissue destruction. uPA is a potent marker of invasion and metastasis in a variety of human cancers including breast, stomach, colon, bladder, ovarian, brain, and endometrium.
Product Specifications
Synonyms
PLAU; ATF; QPD; UPA; URK; u-PA; BDPLT5
NCBI Gene ID
5328
UniProt
P00749
Accession Number
NP_002649.1
Accession Number mRNA
NM_002658.3
Chromosomal Location
10q24
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human uPA
Clone
(#8G26)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2
Curated Selection
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