TNFSF18 (GITR Ligand)
GITR Ligand (GITRL) is a member of the TNF superfamily and has been designated TNFSF18. The carboxy-terminal extracellular domain shows sequence similarily to TNF-alpha/TNFSF1A, Fas Ligand/TNFSF6, TRAIL/TNFSF10, and TNF-beta/TNFSF1B. GITRL is constitutively expressed in human umbilical vein endothelial cells but is not expressed in resting or stimulated T cell lines, B cell lines or peripheral blood mononuclear cells.
Product Specifications
Synonyms
TNFSF18; TL6; AITRL; GITRL; hGITRL
NCBI Gene ID
8995
UniProt
Q9UNG2
Accession Number
NP_005083.2
Accession Number mRNA
NM_005092.3
Chromosomal Location
1q23
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant TNFSF18 EC domain
Clone
(#4Q25)
Applications
FC, N, Detection Ab
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG1
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