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TNFSF18 (GITR Ligand)

GITR Ligand (GITRL) is a member of the TNF superfamily and has been designated TNFSF18. The carboxy-terminal extracellular domain shows sequence similarily to TNF-alpha/TNFSF1A, Fas Ligand/TNFSF6, TRAIL/TNFSF10, and TNF-beta/TNFSF1B. GITRL is constitutively expressed in human umbilical vein endothelial cells but is not expressed in resting or stimulated T cell lines, B cell lines or peripheral blood mononuclear cells.

Product Specifications

Synonyms

TNFSF18; TL6; AITRL; GITRL; hGITRL

NCBI Gene ID

8995

UniProt

Q9UNG2

Accession Number

NP_005083.2

Accession Number mRNA

NM_005092.3

Chromosomal Location

1q23

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Human recombinant TNFSF18 EC domain

Clone

(#4Q25)

Applications

FC, N, Detection Ab

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Host or Source

Mouse

Isotype

IgG1

Frequently Asked Questions

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