TNFSF13B (BAFF)
BAFF (B cell activating factor), also known as BlyS (B lymphocyte stimulator) and TALL-1 (TNF- and APOL-related leukocyte expressed ligand 1) is a member of the TNF superfamily designated TNFSF13B. BAFF is expressed by monocytes and dendritic cells in the form of a membrane-anchored homotrimer which may be shed from the cell surface by Furin. BAFF binds BAFF R/TNFRSF13C, BCMA/TNFRSF17 and TACI/TNFRSF13B receptors to regulate B cell homeostasis.
Product Specifications
Synonyms
TNFSF13B; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
NCBI Gene ID
10673
UniProt
Q9Y275
Accession Number
NP_006564.1
Accession Number mRNA
NM_006573.4
Chromosomal Location
13q32-q34
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant TNFSF13B (EC domain)
Clone
(#8K16)
Applications
WB, FC
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG1
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