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TNFSF11 (TRANCE)

TNF-related activation-induced cytokines (TRANCE), also called RANK Ligand (RANKL, receptor activator of NF-kB ligand), osteoprotegerin ligand (OPGL), and osteoclast differentiation factor (ODF), is a member of the TNF superfamily. Mouse and human TRANCE share 85% amino acid sequence identity. TRANCE is primarily expressed in T cells and T cell rich organs, such as thymus and lymph nodes.

Product Specifications

Synonyms

TNFSF11; ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TRANCE; hRANKL2

NCBI Gene ID

8600

UniProt

O14788

Accession Number

NP_003692.1

Accession Number mRNA

NM_003701.3

Chromosomal Location

13q14

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Human recombinant TNFSF11 (TRANCE)

Clone

(#5G33)

Applications

N, IHC

Purification Method

Protein G chromatography

Assay Protocol

Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

Host or Source

Mouse

Isotype

IgG2

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