TNFSF10
TNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members. Among TNF superfamily members, TRAIL is the most homologous to Fas Ligand, sharing 28% amino acid sequence identity in their extracellular domains. Human TRAIL shares 65% amino acid sequence identity with mouse TRAIL and is active on mouse cells.
Product Specifications
Synonyms
TNFSF10; TL2; APO2L; CD253; TRAIL; Apo-2L
NCBI Gene ID
8743
UniProt
P50591
Accession Number
NP_00380.1
Accession Number mRNA
NM_003810.3
Chromosomal Location
3q26
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human TNFSF10
Clone
(#5A24)
Applications
Capture Ab
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG1
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