TNFRSF17 (BCMA)
B cell maturation protein (BCMA) is a member of the TNF receptor superfamily (TNFRSF17) . BCMA is expressed in immune organs and mature B cell lines. Although some expression has been observed at the cell surface, BCMA appears to be localized to the Golgi compartment. BCMA binding to APRIL or BAFF stimulates IgM production in peripheral blood B cells and increases the survival of cultured B cells. Mature human and mouse BCMA share 86% amino acid sequence identity.
Product Specifications
Synonyms
TNFRSF17; BCM; BCMA; CD269
NCBI Gene ID
608
UniProt
Q02223
Accession Number
NP_001183.2
Accession Number mRNA
NM_001192.2
Chromosomal Location
16p13.1
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human TNFRSF17 EC domain
Clone
(#3D44)
Applications
WB, Blocking
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Rat
Isotype
IgG2
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