TNFRSF9

4-1BB is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is alternatively known as TNFRSF9, CD137, and ILA. The human and mouse proteins share 60% amino acid sequence identity. 4-1BB is absent from naive T cells, but it is upregulated and continually expressed following T cell activation.

Product Specifications

Synonyms

Tnfrsf9; ILA; Ly63; 4-1BB; Cd137; CDw137; AA408498; AI325004; A930040I11Rik

NCBI Gene ID

21942

UniProt

P20334

Accession Number

NP_035742.1

Accession Number mRNA

NM_011612.2

Chromosomal Location

4 E2; 4 75.5 cM

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Mouse recombinant 4-1BB EC-domain

Clone

(#4G33)

Applications

FC, WB

Purification Method

Protein A/G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.